Epione.

Epoione (Ἠπιόνη) (Ēpiónē) was a wife of Asclepius in Greek myths and legends. She was the goddess of the soothing of pain.

Machaon, Podalirius, Panacea, Hygieia, Iaso, Aceso, and Aegle were their children.

There are different types of art that show Epione.

Iaso.

Iaso (Ἰησώ) (Iēsō) was one of the goddesses of medicine in Greek myths and legends. Asclepius and Epione were her parents.

Panacea, Hygieia, Aceso, and Aegle were Iaso's sisters. Machaon, Telesphorus (Τελεσφόρος) (Telesphoros), and Podalirius were her brothers.

There are different stories about Iaso.

Machaon.

Machaon was a surgeon in Greek myths and legends. His parents were Asclepius and Epione.

Asclepius' son and his brother Podalirius took part in the Trojan War.

Machaon was killed by Penthesilea (Πενθεσίλεια) (Penthesíleia).

Hygieia, Panacea, Iaso, Aceso, and Aegle (Αἴγλη) were his siblings.

Also, Machaon had several children.

Panacea.

Panacea (Πανάκεια) was a goddess of healing in Greek mythology. Asclepius (Ἀσκληπιός) (Aesculapius) was her father and Epione (Ἠπιόνη) (Ēpiónē) her mother.

Machaon (Μαχάων) (Macháōn) and Podalirius (Ποδαλείριος) were Panacea's brothers. Hygieia (Ὑγιεία) (Hygēa), Iaso (Ἰασώ), and Aceso (Ἀκεσώ) (Akesó) were her sisters.

Panacea had the ability to transform ordinary plants into medicines. She and her father Asclepius helped warriors during battles.

The word "panacea" figuratively means "a cure for all diseases".

Hygieia.

Hygieia (Ὑγεία) was a goddess of health and cleanness in Ancient Greece. Her parents were Asclepius and Epione. Hygieia had several sisters: Panacea, Iaso, Aceso, and Aglaea.

She had her own symbol called bowl of Hygieia which is a cup with intertwined snake. Now this is the symbol of pharmacy.

Hygieia's father Asclepius was important for her. They had similar cults.

There are many paintings and sculptures about goddess Hygieia. The word "hygiene" appeared from the goddess's name.